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Functional decline at the aging neuromuscular junction is associated with altered laminin-α4 expression

Laminin-α4 is involved in the alignment of active zones to postjunctional folds at the neuromuscular junction (NMJ). Prior study has implicated laminin-α4 in NMJ maintenance, with altered NMJ morphology observed in adult laminin-α4 deficient mice (lama4(−/−)). The present study further investigated...

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Detalles Bibliográficos
Autores principales: Lee, Kah Meng, Chand, Kirat K., Hammond, Luke A., Lavidis, Nickolas A., Noakes, Peter G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391237/
https://www.ncbi.nlm.nih.gov/pubmed/28301326
http://dx.doi.org/10.18632/aging.101198