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APOE ε4 specific imbalance of arachidonic acid and docosahexaenoic acid in serum phospholipids identifies individuals with preclinical Mild Cognitive Impairment/Alzheimer's Disease

This study was designed to explore the influence of apolipoprotein E (APOE) on blood phospholipids (PL) in predicting preclinical Alzheimer's disease (AD). Lipidomic analyses were also performed on blood from an AD mouse model expressing human APOE isoforms (EFAD) and five AD mutations and from...

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Detalles Bibliográficos
Autores principales: Abdullah, Laila, Evans, James E, Emmerich, Tanja, Crynen, Gogce, Shackleton, Ben, Keegan, Andrew P, Luis, Cheryl, Tai, Leon, LaDu, Mary J, Mullan, Michael, Crawford, Fiona, Bachmeier, Corbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391242/
https://www.ncbi.nlm.nih.gov/pubmed/28333036
http://dx.doi.org/10.18632/aging.101203