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APOE ε4 specific imbalance of arachidonic acid and docosahexaenoic acid in serum phospholipids identifies individuals with preclinical Mild Cognitive Impairment/Alzheimer's Disease
This study was designed to explore the influence of apolipoprotein E (APOE) on blood phospholipids (PL) in predicting preclinical Alzheimer's disease (AD). Lipidomic analyses were also performed on blood from an AD mouse model expressing human APOE isoforms (EFAD) and five AD mutations and from...
Autores principales: | Abdullah, Laila, Evans, James E, Emmerich, Tanja, Crynen, Gogce, Shackleton, Ben, Keegan, Andrew P, Luis, Cheryl, Tai, Leon, LaDu, Mary J, Mullan, Michael, Crawford, Fiona, Bachmeier, Corbin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391242/ https://www.ncbi.nlm.nih.gov/pubmed/28333036 http://dx.doi.org/10.18632/aging.101203 |
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