Decoding cyclase-dependent assembly of hapalindole and fischerindole alkaloids

The formation of C-C bonds in an enantioselective fashion to create complex polycyclic scaffolds in the hapalindole/fischerindole type alkaloids from Stigonematales cyanobacteria represents a compelling and urgent challenge in adapting microbial biosynthesis as a catalytic platform in drug developme...

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Detalles Bibliográficos
Autores principales: Li, Shasha, Lowell, Andrew N., Newmister, Sean A., Yu, Fengan, Williams, Robert M., Sherman, David H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391265/
https://www.ncbi.nlm.nih.gov/pubmed/28288107
http://dx.doi.org/10.1038/nchembio.2327

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391265/
https://www.ncbi.nlm.nih.gov/pubmed/28288107
http://dx.doi.org/10.1038/nchembio.2327

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