Peptide Macrocyclization Inspired by Non-Ribosomal Imine Natural Products

[Image: see text] A thermodynamic approach to peptide macrocyclization inspired by the cyclization of non-ribosomal peptide aldehydes is presented. The method provides access to structurally diverse macrocycles by exploiting the reactivity of transient macrocyclic peptide imines toward inter- and in...

Descripción completa

Detalles Bibliográficos
Autores principales: Malins, Lara R., deGruyter, Justine N., Robbins, Kevin J., Scola, Paul M., Eastgate, Martin D., Ghadiri, M. Reza, Baran, Phil S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391502/
https://www.ncbi.nlm.nih.gov/pubmed/28326777
http://dx.doi.org/10.1021/jacs.7b01624

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391502/
https://www.ncbi.nlm.nih.gov/pubmed/28326777
http://dx.doi.org/10.1021/jacs.7b01624

Ejemplares similares