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Peptide Macrocyclization Inspired by Non-Ribosomal Imine Natural Products
[Image: see text] A thermodynamic approach to peptide macrocyclization inspired by the cyclization of non-ribosomal peptide aldehydes is presented. The method provides access to structurally diverse macrocycles by exploiting the reactivity of transient macrocyclic peptide imines toward inter- and in...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391502/ https://www.ncbi.nlm.nih.gov/pubmed/28326777 http://dx.doi.org/10.1021/jacs.7b01624 |