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Comparison of different cell type correction methods for genome-scale epigenetics studies

BACKGROUND: Whole blood is frequently utilized in genome-wide association studies of DNA methylation patterns in relation to environmental exposures or clinical outcomes. These associations can be confounded by cellular heterogeneity. Algorithms have been developed to measure or adjust for this hete...

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Detalles Bibliográficos
Autores principales: Kaushal, Akhilesh, Zhang, Hongmei, Karmaus, Wilfried J. J., Ray, Meredith, Torres, Mylin A., Smith, Alicia K., Wang, Shu-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391562/
https://www.ncbi.nlm.nih.gov/pubmed/28410574
http://dx.doi.org/10.1186/s12859-017-1611-2