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Comparison of different cell type correction methods for genome-scale epigenetics studies
BACKGROUND: Whole blood is frequently utilized in genome-wide association studies of DNA methylation patterns in relation to environmental exposures or clinical outcomes. These associations can be confounded by cellular heterogeneity. Algorithms have been developed to measure or adjust for this hete...
Autores principales: | Kaushal, Akhilesh, Zhang, Hongmei, Karmaus, Wilfried J. J., Ray, Meredith, Torres, Mylin A., Smith, Alicia K., Wang, Shu-Li |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391562/ https://www.ncbi.nlm.nih.gov/pubmed/28410574 http://dx.doi.org/10.1186/s12859-017-1611-2 |
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