Study of SV40 large T antigen nucleotide specificity for DNA unwinding

BACKGROUND: Simian Virus 40 (SV40) Large Tumor Antigen (LT) is an essential enzyme that plays a vital role in viral DNA replication in mammalian cells. As a replicative helicase and initiator, LT assembles as a double-hexamer at the SV40 origin to initiate genomic replication. In this process, LT co...

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Detalles Bibliográficos
Autores principales: Wang, Damian, Álvarez-Cabrera, Ana Lucia, Chen, Xiaojiang S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391581/
https://www.ncbi.nlm.nih.gov/pubmed/28410592
http://dx.doi.org/10.1186/s12985-017-0733-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391581/
https://www.ncbi.nlm.nih.gov/pubmed/28410592
http://dx.doi.org/10.1186/s12985-017-0733-5

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