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Mu-opioid receptor and delta-opioid receptor differentially regulate microglial inflammatory response to control proopiomelanocortin neuronal apoptosis in the hypothalamus: effects of neonatal alcohol

BACKGROUND: Opioid receptors are known to control neurotransmission of various peptidergic neurons, but their potential role in regulation of microglia and neuronal cell communications is unknown. We investigated the role of mu-opioid receptors (MOR) and delta-opioid receptors (DOR) on microglia in...

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Detalles Bibliográficos
Autores principales: Shrivastava, Pallavi, Cabrera, Miguel A., Chastain, Lucy G., Boyadjieva, Nadka I., Jabbar, Shaima, Franklin, Tina, Sarkar, Dipak K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391607/
https://www.ncbi.nlm.nih.gov/pubmed/28407740
http://dx.doi.org/10.1186/s12974-017-0844-3