Toll-like receptor 4 in glial inflammatory responses to air pollution in vitro and in vivo

BACKGROUND: Exposure to traffic-related air pollution (TRAP) is associated with accelerated cognitive aging and higher dementia risk in human populations. Rodent brains respond to TRAP with activation of astrocytes and microglia, increased inflammatory cytokines, and neurite atrophy. A role for Toll...

Descripción completa

Detalles Bibliográficos
Autores principales: Woodward, Nicholas C., Levine, Morgan C., Haghani, Amin, Shirmohammadi, Farimah, Saffari, Arian, Sioutas, Constantinos, Morgan, Todd E., Finch, Caleb E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391610/
https://www.ncbi.nlm.nih.gov/pubmed/28410596
http://dx.doi.org/10.1186/s12974-017-0858-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391610/
https://www.ncbi.nlm.nih.gov/pubmed/28410596
http://dx.doi.org/10.1186/s12974-017-0858-x

Ejemplares similares