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Toll-like receptor 4 in glial inflammatory responses to air pollution in vitro and in vivo

BACKGROUND: Exposure to traffic-related air pollution (TRAP) is associated with accelerated cognitive aging and higher dementia risk in human populations. Rodent brains respond to TRAP with activation of astrocytes and microglia, increased inflammatory cytokines, and neurite atrophy. A role for Toll...

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Detalles Bibliográficos
Autores principales:	Woodward, Nicholas C., Levine, Morgan C., Haghani, Amin, Shirmohammadi, Farimah, Saffari, Arian, Sioutas, Constantinos, Morgan, Todd E., Finch, Caleb E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391610/ https://www.ncbi.nlm.nih.gov/pubmed/28410596 http://dx.doi.org/10.1186/s12974-017-0858-x

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