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Direct imaging of APP proteolysis in living cells

Alzheimer’s disease is a multifactorial disorder caused by the interaction of genetic, epigenetic and environmental factors. The formation of cytotoxic oligomers consisting of Aβ peptide is widely accepted as being one of the main key events triggering the development of Alzheimer’s disease. Aβ pept...

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Detalles Bibliográficos
Autores principales: Parenti, Niccoló, Del Grosso, Ambra, Antoni, Claudia, Cecchini, Marco, Corradetti, Renato, Pavone, Francesco S., Calamai, Martino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391788/
https://www.ncbi.nlm.nih.gov/pubmed/28413720
http://dx.doi.org/10.7717/peerj.3086