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The identification of protein domains that mediate functional interactions between Rab-GTPases and RabGAPs using 3D protein modeling
Currently, time-consuming serial in vitro experimentation involving immunocytochemistry or radiolabeled materials is required to identify which of the numerous Rab-GTPases (Rab) and Rab-GTPase activating proteins (RabGAP) are capable of functional interactions. These interactions are essential for n...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391865/ https://www.ncbi.nlm.nih.gov/pubmed/28435300 http://dx.doi.org/10.2147/AABC.S121245 |