The identification of protein domains that mediate functional interactions between Rab-GTPases and RabGAPs using 3D protein modeling

Currently, time-consuming serial in vitro experimentation involving immunocytochemistry or radiolabeled materials is required to identify which of the numerous Rab-GTPases (Rab) and Rab-GTPase activating proteins (RabGAP) are capable of functional interactions. These interactions are essential for n...

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Detalles Bibliográficos
Autores principales: Davie, Jeremiah J, Faitar, Silviu L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391865/
https://www.ncbi.nlm.nih.gov/pubmed/28435300
http://dx.doi.org/10.2147/AABC.S121245

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