A bis-sulphamoylated estradiol derivative induces ROS-dependent cell cycle abnormalities and subsequent apoptosis

Clinical trials have revealed that the potential anticancer agent, 2-methoxyestradiol (2ME2) has limitations due to its low bioavailability. Subsequently, 2ME2 derivatives including (8R,13S,14S,17S)-2-ethyl-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrane-3,17-diyl bis(sul...

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Detalles Bibliográficos
Autores principales: Visagie, Michelle Helen, van den Bout, Iman, Joubert, Anna Margaretha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391954/
https://www.ncbi.nlm.nih.gov/pubmed/28410397
http://dx.doi.org/10.1371/journal.pone.0176006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391954/
https://www.ncbi.nlm.nih.gov/pubmed/28410397
http://dx.doi.org/10.1371/journal.pone.0176006

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