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Effects of contact structure on the transient evolution of HIV virulence

Early in an epidemic, high densities of susceptible hosts select for relatively high parasite virulence; later in the epidemic, lower susceptible densities select for lower virulence. Thus over the course of a typical epidemic the average virulence of parasite strains increases initially, peaks part...

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Detalles Bibliográficos
Autores principales: Park, Sang Woo, Bolker, Benjamin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391972/
https://www.ncbi.nlm.nih.gov/pubmed/28362805
http://dx.doi.org/10.1371/journal.pcbi.1005453