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Hepatocyte Growth Factor/C-Met Axis in Thyroid Cancer: From Diagnostic Biomarker to Therapeutic Target

The hepatocyte growth factor (HGF)/c-met axis plays a crucial role in cancer development by promoting cellular proliferation, motility, and morphogenesis, as well as angiogenesis. Different cellular distributions of both the ligand and the receptor in benign vs malignant lesions indicate this biolog...

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Detalles Bibliográficos
Autores principales: Trovato, Maria, Campennì, Alfredo, Giovinazzo, Salvatore, Siracusa, Massimiliano, Ruggeri, Rosaria Maddalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391983/
https://www.ncbi.nlm.nih.gov/pubmed/28469401
http://dx.doi.org/10.1177/1177271917701126