Real-Time Reverse-Transcription Quantitative Polymerase Chain Reaction Assay Is a Feasible Method for the Relative Quantification of Heregulin Expression in Non–Small Cell Lung Cancer Tissue

In preclinical studies, heregulin (HRG) expression was shown to be the most relevant predictive biomarker for response to patritumab, a fully human anti–epidermal growth factor receptor 3 monoclonal antibody. In support of a phase 2 study of erlotinib ± patritumab in non–small cell lung cancer (NSCL...

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Detalles Bibliográficos
Autores principales: Kristof, Jessica, Sakrison, Kellen, Jin, Xiaoping, Nakamaru, Kenji, Schneider, Matthias, Beckman, Robert A, Freeman, Daniel, Spittle, Cindy, Feng, Wenqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391987/
https://www.ncbi.nlm.nih.gov/pubmed/28469400
http://dx.doi.org/10.1177/1177271917699850

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391987/
https://www.ncbi.nlm.nih.gov/pubmed/28469400
http://dx.doi.org/10.1177/1177271917699850

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