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Significant Prognostic Features and Patterns of Somatic TP53 Mutations in Human Cancers
TP53 is the most frequently altered gene in human cancers. Numerous retrospective studies have related its mutation and abnormal p53 protein expression to poor patient survival. Nonetheless, the clinical significance of TP53 (p53) status has been a controversial issue. In this work, we aimed to char...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392013/ https://www.ncbi.nlm.nih.gov/pubmed/28469388 http://dx.doi.org/10.1177/1176935117691267 |