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Significant Prognostic Features and Patterns of Somatic TP53 Mutations in Human Cancers

TP53 is the most frequently altered gene in human cancers. Numerous retrospective studies have related its mutation and abnormal p53 protein expression to poor patient survival. Nonetheless, the clinical significance of TP53 (p53) status has been a controversial issue. In this work, we aimed to char...

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Detalles Bibliográficos
Autores principales: Zhang, Wensheng, Edwards, Andrea, Flemington, Erik K, Zhang, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392013/
https://www.ncbi.nlm.nih.gov/pubmed/28469388
http://dx.doi.org/10.1177/1176935117691267