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Studying dyadic structure–function relationships: a review of current modeling approaches and new insights into Ca(2+) (mis)handling

Excitation–contraction coupling in cardiac myocytes requires calcium influx through L-type calcium channels in the sarcolemma, which gates calcium release through sarcoplasmic reticulum ryanodine receptors in a process known as calcium-induced calcium release, producing a myoplasmic calcium transien...

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Detalles Bibliográficos
Autores principales: Maleckar, Mary M, Edwards, Andrew G, Louch, William E, Lines, Glenn T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392018/
https://www.ncbi.nlm.nih.gov/pubmed/28469494
http://dx.doi.org/10.1177/1179546817698602