Role of Transporters in Central Nervous System Drug Delivery and Blood-Brain Barrier Protection: Relevance to Treatment of Stroke

Ischemic stroke is a leading cause of morbidity and mortality in the United States. The only approved pharmacologic treatment for ischemic stroke is thrombolysis via recombinant tissue plasminogen activator (r-tPA). A short therapeutic window and serious adverse events (ie, hemorrhage, excitotoxicit...

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Detalles Bibliográficos
Autores principales: Brzica, Hrvoje, Abdullahi, Wazir, Ibbotson, Kathryn, Ronaldson, Patrick T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392046/
https://www.ncbi.nlm.nih.gov/pubmed/28469523
http://dx.doi.org/10.1177/1179573517693802

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392046/
https://www.ncbi.nlm.nih.gov/pubmed/28469523
http://dx.doi.org/10.1177/1179573517693802

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