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Role of Transporters in Central Nervous System Drug Delivery and Blood-Brain Barrier Protection: Relevance to Treatment of Stroke
Ischemic stroke is a leading cause of morbidity and mortality in the United States. The only approved pharmacologic treatment for ischemic stroke is thrombolysis via recombinant tissue plasminogen activator (r-tPA). A short therapeutic window and serious adverse events (ie, hemorrhage, excitotoxicit...
Autores principales: | Brzica, Hrvoje, Abdullahi, Wazir, Ibbotson, Kathryn, Ronaldson, Patrick T |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392046/ https://www.ncbi.nlm.nih.gov/pubmed/28469523 http://dx.doi.org/10.1177/1179573517693802 |
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