CaMKII inhibition reduces isoproterenol-induced ischemia and arrhythmias in hypertrophic mice

OBJECTIVES: The Ca/calmodulin-dependent protein kinase II (CaMKII), an arrhythmogenic molecule, is excessively activated in cardiac hypertrophy. Here, we investigated the effect of CaMKII inhibition in isoproterenol (ISO)-induced arrhythmias in hypertrophic mice. RESULTS: ISO induced multiple types...

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Detalles Bibliográficos
Autores principales: Feng, Ying, Cheng, Jun, Wei, Baozhu, Wang, Yanggan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper: Pathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392265/
https://www.ncbi.nlm.nih.gov/pubmed/28177919
http://dx.doi.org/10.18632/oncotarget.15099

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392265/
https://www.ncbi.nlm.nih.gov/pubmed/28177919
http://dx.doi.org/10.18632/oncotarget.15099

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