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CaMKII inhibition reduces isoproterenol-induced ischemia and arrhythmias in hypertrophic mice
OBJECTIVES: The Ca/calmodulin-dependent protein kinase II (CaMKII), an arrhythmogenic molecule, is excessively activated in cardiac hypertrophy. Here, we investigated the effect of CaMKII inhibition in isoproterenol (ISO)-induced arrhythmias in hypertrophic mice. RESULTS: ISO induced multiple types...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392265/ https://www.ncbi.nlm.nih.gov/pubmed/28177919 http://dx.doi.org/10.18632/oncotarget.15099 |