The interference of Notch1 target Hes1 affects cell growth, differentiation and invasiveness of glioblastoma stem cells through modulation of multiple oncogenic targets

The invasive and lethal nature of Glioblastoma multiforme (GBM) necessitates the continuous identification of molecular targets and search of efficacious therapies to inhibit GBM growth. The GBM resistance to chemotherapy and radiation it is attributed to the existence of a rare fraction of cancer s...

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Detalles Bibliográficos
Autores principales: Cenciarelli, Carlo, Marei, Hany E., Zonfrillo, Manuela, Casalbore, Patrizia, Felsani, Armando, Giannetti, Stefano, Trevisi, Gianluca, Althani, Asma, Mangiola, Annunziato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392293/
https://www.ncbi.nlm.nih.gov/pubmed/28157712
http://dx.doi.org/10.18632/oncotarget.15013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392293/
https://www.ncbi.nlm.nih.gov/pubmed/28157712
http://dx.doi.org/10.18632/oncotarget.15013

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