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The natural compound fucoidan from New Zealand Undaria pinnatifida synergizes with the ERBB inhibitor lapatinib enhancing melanoma growth inhibition

Melanoma remains one of the most aggressive and therapy-resistant cancers. Finding new treatments to improve patient outcomes is an ongoing effort. We previously demonstrated that melanoma relies on the activation of ERBB signaling, specifically of the ERBB3/ERBB2 cascade. Here we show that melanoma...

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Detalles Bibliográficos
Autores principales: Thakur, Varsha, Lu, Jun, Roscilli, Giuseppe, Aurisicchio, Luigi, Cappelletti, Manuela, Pavoni, Emiliano, White, William Lindsey, Bedogni, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392294/
https://www.ncbi.nlm.nih.gov/pubmed/28060735
http://dx.doi.org/10.18632/oncotarget.14437