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Loss of PFKFB4 induces cell death in mitotically arrested ovarian cancer cells

Taxanes represent some of the most commonly used chemotherapeutic agents for ovarian cancer treatment. However, they are only effective in approximately 40% of patients. Novel therapeutic strategies are required to potentiate their effect and improve patient outcome. A hallmark of many cancers is th...

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Detalles Bibliográficos
Autores principales: Taylor, Charlotte, Mannion, David, Mirand a, Fabrizio, Karaminejadranjbar, Mohammad, Herrero-Gonzalez, Sandra, Hellner, Karin, Zheng, Yiyan, Bartholomeusz, Geoffrey, Bast, Robert C., Ahmed, Ahmed Ashour
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392300/
https://www.ncbi.nlm.nih.gov/pubmed/28152500
http://dx.doi.org/10.18632/oncotarget.14910