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KRAS-dependent suppression of MYC enhances the sensitivity of cancer cells to cytotoxic agents
KRAS is the most commonly mutated oncogene, frequently associated with some of the deadliest forms of cancer. However, the need for potent and specific KRAS inhibitors remains unmet. Here, we evaluated the effects of selected cytotoxic agents on oncogenic KRAS signaling and drug response. The data p...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392302/ https://www.ncbi.nlm.nih.gov/pubmed/28152508 http://dx.doi.org/10.18632/oncotarget.14929 |