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Small G protein Rac GTPases regulate the maintenance of glioblastoma stem-like cells in vitro and in vivo
Glioblastoma is the most common and aggressive malignant brain tumor in adults. The existence of glioblastoma stem cells (GSCs) or stem–like cells (stemloids) may account for its invasiveness and high recurrence. Rac proteins belong to the Rho small GTPase subfamily which regulates cell movement, pr...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392305/ https://www.ncbi.nlm.nih.gov/pubmed/28160553 http://dx.doi.org/10.18632/oncotarget.14949 |