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Small G protein Rac GTPases regulate the maintenance of glioblastoma stem-like cells in vitro and in vivo

Glioblastoma is the most common and aggressive malignant brain tumor in adults. The existence of glioblastoma stem cells (GSCs) or stem–like cells (stemloids) may account for its invasiveness and high recurrence. Rac proteins belong to the Rho small GTPase subfamily which regulates cell movement, pr...

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Detalles Bibliográficos
Autores principales: Lai, Yun-Ju, Tsai, Jui-Cheng, Tseng, Ying-Ting, Wu, Meng-Shih, Liu, Wen-Shan, Lam, Hoi-Ian, Yu, Jei-Hwa, Nozell, Susan E., Benveniste, Etty N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392305/
https://www.ncbi.nlm.nih.gov/pubmed/28160553
http://dx.doi.org/10.18632/oncotarget.14949