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OIP5, a target of miR-15b-5p, regulates hepatocellular carcinoma growth and metastasis through the AKT/mTORC1 and β-catenin signaling pathways

Opa interacting protein 5 (OIP5) is upregulated in some types of human cancers, but the biological implications of its upregulation have not yet been clarified in human hepatocellular carcinoma (HCC). In this study, the signaling pathway downstream of OIP5 was analyzed by proteome kinase profiling....

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Detalles Bibliográficos
Autores principales: Li, Hua, Zhang, Jun, Lee, Mi-Jin, Yu, Goung-Ran, Han, Xueji, Kim, Dae-Ghon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392313/
https://www.ncbi.nlm.nih.gov/pubmed/28184024
http://dx.doi.org/10.18632/oncotarget.15185