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Allele specific synthetic lethality between priC and dnaA(ts )alleles at the permissive temperature of 30°C in E. coli K-12
BACKGROUND: DnaA is an essential protein in the regulation and initiation of DNA replication in many bacteria. It forms a protein-DNA complex at oriC to which DnaC loads DnaB. DNA replication forks initiated at oriC by DnaA can collapse on route to the terminus for a variety of reasons. PriA, PriB,...
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2004
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC539235/ https://www.ncbi.nlm.nih.gov/pubmed/15588282 http://dx.doi.org/10.1186/1471-2180-4-47 |