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BAG-1 haplo-insufficiency impairs lung tumorigenesis
BACKGROUND: BAG-1 is a multifunctional co-chaperone of heat shock proteins (Hsc70/Hsp70) that is expressed in most cells. It interacts with Bcl-2 and Raf indicating that it might connect protein folding with other signaling pathways. Evidence that BAG-1 expression is frequently altered in human canc...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC539250/ https://www.ncbi.nlm.nih.gov/pubmed/15560850 http://dx.doi.org/10.1186/1471-2407-4-85 |