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BAG-1 haplo-insufficiency impairs lung tumorigenesis

BACKGROUND: BAG-1 is a multifunctional co-chaperone of heat shock proteins (Hsc70/Hsp70) that is expressed in most cells. It interacts with Bcl-2 and Raf indicating that it might connect protein folding with other signaling pathways. Evidence that BAG-1 expression is frequently altered in human canc...

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Detalles Bibliográficos
Autores principales: Götz, Rudolf, Kramer, Boris W, Camarero, Guadalupe, Rapp, Ulf R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC539250/
https://www.ncbi.nlm.nih.gov/pubmed/15560850
http://dx.doi.org/10.1186/1471-2407-4-85