Over expression of the selectable marker blasticidin S deaminase gene is toxic to human keratinocytes and murine BALB/MK cells

BACKGROUND: The blasticidin S resistance gene (bsr) is a selectable marker used for gene transfer experiments. The bsr gene encodes for blasticidin S (BS) deaminase, which has a specific activity upon BS. Therefore, its expression is supposed to be harmless in cells. The work reported on herein cons...

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Detalles Bibliográficos
Autores principales: Bento, Fernanda Mara, Takeshita, Daniela, Sacramento, Chester Bittencourt, Machado, Tamara Rocha, Mathor, Monica Beatriz, Carmona, Adriana Karaoglanovic, Han, Sang Won
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC539255/
https://www.ncbi.nlm.nih.gov/pubmed/15575952
http://dx.doi.org/10.1186/1472-6750-4-29

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC539255/
https://www.ncbi.nlm.nih.gov/pubmed/15575952
http://dx.doi.org/10.1186/1472-6750-4-29

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