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Travel and the emergence of high-level drug resistance in Plasmodium falciparum in southwest Uganda: results from a population-based study

BACKGROUND: The I164L mutation on the dhfr gene confers high level resistance to sulfadoxine–pyrimethamine (SP) but it is rare in Africa except in a cluster of reports where prevalence >10% in highland areas of southwest Uganda and eastern Rwanda. The occurrence of the dhfr I164L mutation was inv...

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Detalles Bibliográficos
Autores principales: Lynch, Caroline A., Pearce, Richard, Pota, Hirva, Egwang, Connie, Egwang, Thomas, Bhasin, Amit, Cox, Jonathan, Abeku, Tarekegn A., Roper, Cally
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392983/
https://www.ncbi.nlm.nih.gov/pubmed/28415996
http://dx.doi.org/10.1186/s12936-017-1812-1