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Travel and the emergence of high-level drug resistance in Plasmodium falciparum in southwest Uganda: results from a population-based study
BACKGROUND: The I164L mutation on the dhfr gene confers high level resistance to sulfadoxine–pyrimethamine (SP) but it is rare in Africa except in a cluster of reports where prevalence >10% in highland areas of southwest Uganda and eastern Rwanda. The occurrence of the dhfr I164L mutation was inv...
Autores principales: | Lynch, Caroline A., Pearce, Richard, Pota, Hirva, Egwang, Connie, Egwang, Thomas, Bhasin, Amit, Cox, Jonathan, Abeku, Tarekegn A., Roper, Cally |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392983/ https://www.ncbi.nlm.nih.gov/pubmed/28415996 http://dx.doi.org/10.1186/s12936-017-1812-1 |
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