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Drosophila melanogaster retrotransposon and inverted repeat-derived endogenous siRNAs are differentially processed in distinct cellular locations

BACKGROUND: Endogenous small interfering (esi)RNAs repress mRNA levels and retrotransposon mobility in Drosophila somatic cells by poorly understood mechanisms. 21 nucleotide esiRNAs are primarily generated from retrotransposons and two inverted repeat (hairpin) loci in Drosophila culture cells in a...

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Detalles Bibliográficos
Autores principales: Harrington, Andrew W., McKain, Michael R., Michalski, Daniel, Bauer, Kaylyn M., Daugherty, Joshua M., Steiniger, Mindy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392987/
https://www.ncbi.nlm.nih.gov/pubmed/28415970
http://dx.doi.org/10.1186/s12864-017-3692-8