Discovery and characterization of natural tropolones as inhibitors of the antibacterial target CapF from Staphylococcus aureus

The rapid spread of antibiotic-resistance among pathogenic bacteria poses a serious risk for public health. The search for novel therapeutic strategies and antimicrobial compounds is needed to ameliorate this menace. The bifunctional metalloenzyme CapF is an antibacterial target produced by certain...

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Detalles Bibliográficos
Autores principales: Nakano, Koichiro, Chigira, Takeru, Miyafusa, Takamitsu, Nagatoishi, Satoru, Caaveiro, Jose M. M., Tsumoto, Kouhei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5393024/
https://www.ncbi.nlm.nih.gov/pubmed/26471247
http://dx.doi.org/10.1038/srep15337

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5393024/
https://www.ncbi.nlm.nih.gov/pubmed/26471247
http://dx.doi.org/10.1038/srep15337

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