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Absence of the dermatan sulfate chain of decorin does not affect mouse development

BACKGROUND: In vitro studies suggest that the multiple functions of decorin are related to both its core protein and its dermatan sulfate chain. To determine the contribution of the dermatan sulfate chain to the functional properties of decorin in vivo, a mutant mouse whose decorin lacked a dermatan...

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Detalles Bibliográficos
Autores principales: Moffatt, Pierre, Geng, Yeqing, Lamplugh, Lisa, Nanci, Antonio, Roughley, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5393030/
https://www.ncbi.nlm.nih.gov/pubmed/28412940
http://dx.doi.org/10.1186/s12952-017-0074-3