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Interleukin-1 primes human mesenchymal stem cells towards an anti-inflammatory and pro-trophic phenotype in vitro

BACKGROUND: Inflammation is a key contributor to central nervous system (CNS) injury such as stroke, and is a major target for therapeutic intervention. Effective treatments for CNS injuries are limited and applicable to only a minority of patients. Stem cell-based therapies are increasingly conside...

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Detalles Bibliográficos
Autores principales: Redondo-Castro, Elena, Cunningham, Catriona, Miller, Jonjo, Martuscelli, Licia, Aoulad-Ali, Sarah, Rothwell, Nancy J., Kielty, Cay M., Allan, Stuart M., Pinteaux, Emmanuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5393041/
https://www.ncbi.nlm.nih.gov/pubmed/28412968
http://dx.doi.org/10.1186/s13287-017-0531-4