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Dual functionality of cis-regulatory elements as developmental enhancers and Polycomb response elements

Developmental gene expression is tightly regulated through enhancer elements, which initiate dynamic spatio–temporal expression, and Polycomb response elements (PREs), which maintain stable gene silencing. These two cis-regulatory functions are thought to operate through distinct dedicated elements....

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Detalles Bibliográficos
Autores principales: Erceg, Jelena, Pakozdi, Tibor, Marco-Ferreres, Raquel, Ghavi-Helm, Yad, Girardot, Charles, Bracken, Adrian P., Furlong, Eileen E.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5393054/
https://www.ncbi.nlm.nih.gov/pubmed/28381411
http://dx.doi.org/10.1101/gad.292870.116