The motor activity of DNA2 functions as an ssDNA translocase to promote DNA end resection

DNA2 nuclease–helicase functions in DNA replication and recombination. This requires the nuclease of DNA2, while, in contrast, the role of the helicase activity has been unclear. We now show that the motor activity of both recombinant yeast and human DNA2 promotes efficient degradation of long stret...

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Detalles Bibliográficos
Autores principales: Levikova, Maryna, Pinto, Cosimo, Cejka, Petr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5393063/
https://www.ncbi.nlm.nih.gov/pubmed/28336515
http://dx.doi.org/10.1101/gad.295196.116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5393063/
https://www.ncbi.nlm.nih.gov/pubmed/28336515
http://dx.doi.org/10.1101/gad.295196.116

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