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Simultaneous mapping of active DNA demethylation and sister chromatid exchange in single cells

To understand mammalian active DNA demethylation, various methods have been developed to map the genomic distribution of the demethylation intermediates 5-formylcysotine (5fC) and 5-carboxylcytosine (5caC). However, the majority of these methods requires a large number of cells to begin with. In thi...

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Detalles Bibliográficos
Autores principales: Wu, Xiaoji, Inoue, Azusa, Suzuki, Tsukasa, Zhang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5393065/
https://www.ncbi.nlm.nih.gov/pubmed/28360182
http://dx.doi.org/10.1101/gad.294843.116