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Inducing circular RNA formation using the CRISPR endoribonuclease Csy4

Circular RNAs (circRNAs) are highly stable, covalently closed RNAs that are regulated in a spatiotemporal manner and whose functions are largely unknown. These molecules have the potential to be incorporated into engineered systems with broad technological implications. Here we describe a switch for...

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Detalles Bibliográficos
Autores principales: Borchardt, Erin K., Meganck, Rita M., Vincent, Heather A., Ball, Christopher B., Ramos, Silvia B.V., Moorman, Nathaniel J., Marzluff, William F., Asokan, Aravind
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5393173/
https://www.ncbi.nlm.nih.gov/pubmed/28223408
http://dx.doi.org/10.1261/rna.056838.116