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The structure of an E. coli tRNA(f)(Met) A(1)–U(72) variant shows an unusual conformation of the A(1)–U(72) base pair

Translation initiation in eukaryotes and archaea involves a methionylated initiator tRNA delivered to the ribosome in a ternary complex with e/aIF2 and GTP. Eukaryotic and archaeal initiator tRNAs contain a highly conserved A(1)–U(72) base pair at the top of the acceptor stem. The importance of this...

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Detalles Bibliográficos
Autores principales: Monestier, Auriane, Aleksandrov, Alexey, Coureux, Pierre-Damien, Panvert, Michel, Mechulam, Yves, Schmitt, Emmanuelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5393177/
https://www.ncbi.nlm.nih.gov/pubmed/28143889
http://dx.doi.org/10.1261/rna.057877.116