Advancing viral RNA structure prediction: measuring the thermodynamics of pyrimidine-rich internal loops

Accurate thermodynamic parameters improve RNA structure predictions and thus accelerate understanding of RNA function and the identification of RNA drug binding sites. Many viral RNA structures, such as internal ribosome entry sites, have internal loops and bulges that are potential drug target site...

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Detalles Bibliográficos
Autores principales: Phan, Andy, Mailey, Katherine, Saeki, Jessica, Gu, Xiaobo, Schroeder, Susan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5393185/
https://www.ncbi.nlm.nih.gov/pubmed/28213527
http://dx.doi.org/10.1261/rna.059865.116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5393185/
https://www.ncbi.nlm.nih.gov/pubmed/28213527
http://dx.doi.org/10.1261/rna.059865.116

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