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Advancing viral RNA structure prediction: measuring the thermodynamics of pyrimidine-rich internal loops
Accurate thermodynamic parameters improve RNA structure predictions and thus accelerate understanding of RNA function and the identification of RNA drug binding sites. Many viral RNA structures, such as internal ribosome entry sites, have internal loops and bulges that are potential drug target site...
Autores principales: | Phan, Andy, Mailey, Katherine, Saeki, Jessica, Gu, Xiaobo, Schroeder, Susan J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5393185/ https://www.ncbi.nlm.nih.gov/pubmed/28213527 http://dx.doi.org/10.1261/rna.059865.116 |
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