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A Model of the Statistical Power of Comparative Genome Sequence Analysis

Comparative genome sequence analysis is powerful, but sequencing genomes is expensive. It is desirable to be able to predict how many genomes are needed for comparative genomics, and at what evolutionary distances. Here I describe a simple mathematical model for the common problem of identifying con...

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Detalles Bibliográficos
Autor principal: Eddy, Sean R
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC539325/
https://www.ncbi.nlm.nih.gov/pubmed/15660152
http://dx.doi.org/10.1371/journal.pbio.0030010