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A Model of the Statistical Power of Comparative Genome Sequence Analysis
Comparative genome sequence analysis is powerful, but sequencing genomes is expensive. It is desirable to be able to predict how many genomes are needed for comparative genomics, and at what evolutionary distances. Here I describe a simple mathematical model for the common problem of identifying con...
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Formato: | Texto |
Lenguaje: | English |
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Public Library of Science
2005
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC539325/ https://www.ncbi.nlm.nih.gov/pubmed/15660152 http://dx.doi.org/10.1371/journal.pbio.0030010 |