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Epstein–Barr Virus Lytic Reactivation Activates B Cells Polyclonally and Induces Activation-Induced Cytidine Deaminase Expression: A Mechanism Underlying Autoimmunity and Its Contribution to Graves' Disease

Graves' disease is an autoimmune disease that results in and is the most common cause of hyperthyroidism, and the reactivation of persisting Epstein–Barr virus (EBV) in B lymphocytes induces the differentiation of host B cells into plasma cells. We previously reported that some EBV-infected B c...

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Detalles Bibliográficos
Autores principales: Nagata, Keiko, Kumata, Keisuke, Nakayama, Yuji, Satoh, Yukio, Sugihara, Hirotsugu, Hara, Sayuri, Matsushita, Michiko, Kuwamoto, Satoshi, Kato, Masako, Murakami, Ichiro, Hayashi, Kazuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5393416/
https://www.ncbi.nlm.nih.gov/pubmed/28333576
http://dx.doi.org/10.1089/vim.2016.0179