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The ET-1-mediated carbonylation and degradation of ANXA1 induce inflammatory phenotype and proliferation of pulmonary artery smooth muscle cells in HPS

Hepatopulmonary syndrome (HPS) is a serious complication of advanced liver disease, which markedly increases mortality. Pulmonary vascular remodelling (PVR) induced by circulating mediators plays an important role in the pathogenesis of HPS, while the underlying mechanism remains undefined. In the p...

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Detalles Bibliográficos
Autores principales: He, Jing, Yi, Bin, Chen, Yang, Huang, Qing, Wang, Huan, Lu, Kaizhi, Fu, Weiling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5393570/
https://www.ncbi.nlm.nih.gov/pubmed/28414743
http://dx.doi.org/10.1371/journal.pone.0175443